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Research Clinical Trials Clinical Trials      
Scientific Research
Clinical Trials Report or Abstract

Clinical Trials and Research undertaken into the Buteyko Method and related issues.

Asthma exacerbations in children immediately following stressful life events: a Cox's heirarchical regression
Source: S Sandberg, S Jarvenpaa, A Penttinen, J Y Paton, and D C McCann Thorax 2004;59 1046-1051 [Full Text]

Background: A recent prospective study of children with asthma employing a within subject, over time analysis using dynamic logistic regression showed that severely negative life events significantly increased the risk of an acute exacerbation during the subsequent 6 week period. The timing of the maximum risk depended on the degree of chronic psychosocial stress also present. A hierarchical Cox regression analysis was undertaken to examine whether there were any immediate effects of negative life events in children without a background of high chronic stress.

Methods: Sixty children with verified chronic asthma were followed prospectively for 18 months with continuous monitoring of asthma by daily symptom diaries and peak flow measurements, accompanied by repeated interview assessments of life events. The key outcome measures were asthma exacerbations and severely negative life events.

Results: An immediate effect evident within the first 2 days following a severely negative life event increased the risk of a new asthma attack by a factor of 4.69 (p = 0.00). In the period 3ľ10 days after a severe event there was no increased risk of an asthma attack (p = 0.5). In addition to the immediate effect, an increased risk of 1.81 was found 5ľ7 weeks after a severe event (p = 0.002). This is consistent with earlier findings. There was a statistically significant variation due to unobserved factors in the incidence of asthma attacks between the children.

Conclusion: The use of statistical methods capable of investigating short time lags showed that stressful life events significantly increase the risk of a new asthma attack immediately after the event; a more delayed increase in risk was also evident 5ľ7 weeks later.

More Clinical Trials

Breathing exercises for asthma: a randomised controlled trial
Thorax 2009; 64:55-61 [Abstract] [Full Text]

A Randomised Controlled Trial of the Buteyko Technique for Asthma Management
Respiratory Medicine May 2008 (Vol. 102, Issue 5, Pages 726-732) [Abstract] [Full Text]

Canadian Buteyko Trial 2008
 [Abstract]

Beta-agonists trigger T cell accumulation
J Allergy Clin Immunol 2006 [Abstract]

Asthma exacerbations in children immediately following stressful life events: a Cox's heirarchical regression
S Sandberg, S Jarvenpaa, A Penttinen, J Y Paton, and D C McCann Thorax 2004;59 1046-1051 [Abstract] [Full Text]

Ventilation Test In Patients With Bronchial Asthma
Buteiko KP, Odintsova MP, Nasonkina NS. Vrach Delo. 1968 Apr; 4:33-6. PMID: 5664602 [PubMed - indexed for MEDLINE] [Abstract]

Obstructive Sleep Apnoea and breathing retraining
Mary Birch, RN,BA,MBioE, Grad Dip Soc, BIBHClinical Update 74, Australian Nursing Journal, August 2004 [Text]

Buteyko Breathing Technique for asthma: an effective intervention
Patrick McHugh, Fergus Aitcheson, Bruce Duncan, Frank Houghton Journal of the New Zealand Medical Association, 12-December-2003, Vol 116 No 1187 [Abstract] [Full Text]

Health Education: Does the Buteyko Institute Method make a difference?
Jill McGowan, Education and training consultant in Asthma Management.Thorax Vol 58, suppl III, page 28, December 2003. [Abstract] [Full Text]

Beta2-Agonist Tolerance and Exercise-induced Bronchospasm
Am. J. Respir. Crit. Care Med., Volume 165, Number 8, April 2002, 1068-1070 RobertáJ. Hancox, Padmaja Subbarao, Dennis Kamada, RichardáM. Watson, FredrickáE. Hargreave, and MarkáD. Inman Asthma Research Group, Firestone Institute for Respiratory Health, McMaster University/St Joseph's Hospital, Hamilton, Ontario, Canada  [Abstract]

End-tidal carbon dioxide measurements as a prognostic indicator of outcome in cardiac arrest.
Ahrens T, Schallom L, Bettorf K, Ellner S, Hurt G, O'Mara V, Ludwig J, George W, Marino T, Shannon W. Barnes-Jewish Hospital, St. Louis, MO, USA. Am J Crit Care 2001 Nov;10(6):391-8 [Abstract]

Repeated Hyperventilation Causes Peripheral Airways Inflammation, Hyperreactivity, and Impaired Bronchodilation in Dogs
MICHAELáS. DAVIS and ARTHURáN. FREED Am. J. Respir. Crit. Care Med., Volume 164, Number 5, September 2001, 785-789 [Abstract]

Cardiovascular side effects of inhaled salbutamol in hypoxic asthmatic patients
Thorax; London; Jul 2001; J Burggraaf; R G J Westendorp; J C C M In't Veen; R C Schoemaker; et al;  [Abstract]

Study explains success of Buteyko
Megan Howe - Australian Doctor, p 20, 11 May 2001 [Text]

Prevalence of dysfunctional breathing in patients treated for asthma in primary care: a cross sectional survey
M Thomas, RK McKinley, E Freeman, C Foy British Medical Journal 2001;322:1098-1100 (5 May) [Abstract]

Hyperventilation and asymptomatic chronic asthma
Thorax; London; Dec 2000; C A Osborne; B J O'Connor; A Lewis; Van Kanabar; W N Gardner; [Abstract]

Buteyko breathing techniques in asthma: a blinded randomised trial
Simon D Bowler, Amanda Green and Charles A Mitchell Medical Journal of Australia 1998; 169:575-578 [Abstract] [Full Text]

Effects of inhaled CO2 and added dead space on idiopathic central sleep apnea
Xje A. Rankin F. Rutherford R. Bradly TD. Journal of Applied Physiology, 82(3):918-26, 1997 Mar. [Abstract]

Changing patterns in asthma morbidity and mortality.
Sears MR J-Investig-Allergol-Clin-Immunol 1995 Mar-Apr; 5(2): 66-72.  [Abstract]

Beneficial effect of inhaled CO2 in a patient with non-obstructive sleep apnoea.
J Neurol 1993 Nov;241(11:45-8 (ISSN: C340-5354) Villiger PM; Hess CW; Reinhart WH Medizinische Klinik der Universitat, Inselspital, Bern, Switzerland [Abstract]

Rediscovering the importance of nasal breathing in sleep or, shut your mouth and save your sleep
Lavie P J Layngol Otol 1987 June;101(6):558-63 [Abstract]

Breathing Patterns
Chest, 1983, 84:202-205Tobin et al (Summary) [Abstract]


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